The term "First Lady" distinguishes the lady of the house from all the rest, simular to the "First Lady of the White House. there are many ladies in the white house but the first lady is the wife of the President of the United States, in the Church House it distinguishes the Pator's Wife from all the other ladies in the church house. This is very important in that it establishes the order of the family in that house. Generally speaking, the first lady of any household should be the mother of that household and the (current) wife of your father.
Giving honor to her is no different from honoring your parents, remember the scripture (children obey your parents in the Lord) identifies spritual parents, as the parents responsible over your spiritual walk with christ. Give honor to whom honor is due.
The responsibilites of the First Lady is distinguished from all other position in the church, because there's so much required of her to keep the ministry afloat, especially when attitudes flare. Generally the first lady of the church has to be in constant communication with the Lord, because if she is not, she would crack up or be quickly committed to the insane assylum, for all that's required of her, and then some. As in any profession, I give honor to whom honor is due, we recongnise Ministers of Music, the mother board, the deacon board, etc..., I personally think it would be very discourteous not to recognize the one who labors with her husband in the untirely in the ministry, as merely some prophetess, or mother on the mother's board, she is the the supporting angel of the house, she can either make her husband's job easy or difficult, depending if she is lead by the Holy Spirit.
Give her, her just due, I would rather say first lady of the house than I would say first man of the house, as I believe this is devine order. As my grandfather and former pastor who's gone on to be with the Lord would say, "it's a poor duck that don't praise it's own pond!"
God Bless,
Robert S. Ellington-Snipes