You probably can get some good tones but it will take some tweaking to disguise the "processed guitar sound" that could be a product of the Digitech.
The biggest thing to watch out for with anything non-tube and/or anything that has modeling technology is it's ability to suck the life and breath from an instrument. The key factors in this is, to me:
1. too much treble
2. too much buzz in the overdrive/distortion
3. too much compression
The general rule for finding good tones is to first use only a decent quality guitar and decent quality amp and it sounds like you've got that (although criticisms are high on Crate amps...some get decent reviews and others not so good) so remove the Digi from the setup and try just your amp and guitar together and see if you can get some good tones going on.
After you've got a good baseline established, THEN put your Digitech in the chain and start tweaking to see if you can improve upon that raw guitar/amp sound.
Do not, I repeat, DO NOT use effects and such to try and get you a good sound from a guitar or amp that's unable to do so by themselves.
Worse case, replace the guitar or amp before you go shuffling around trying to find a new multi-effects device to get you what you want to hear.
Check this out...I just bought a used Epiphone Valve Standard amp...Class A 15 watt all-tube amp...paid $150...after playing it for the last few days I'm ready to toss my Line 6 rig out the window and use the Epi in church. With just my Godin guitar and the Epiphone amp I'm getting sounds that I've NEVER gotten from my Line 6 stuff.
I had forgotten what Class A tube circutry sounded like...even cheap Made in China Class A circutry is sweeeeeet
