lol, sorry for hijacking. It's hard to talk about one setting without talking about others.
The first setting (888000000), is ok. I would use it just when I'm not playing the lead and I want to be smooth, and not too harsh like 8888000000 can be. i will also usually use it with a little of the 1' drawbar just to add some flavor. It would also sound good for some Brooklyn style chords, again with the 1' bar at about 6 maybe with a little reverb if possible. It's not a setting that I use often though.