Abe, I mostly play on the Clean channel. I set the high about 3/4, the mid about half, and the low about 1/4. On the Rythm channel I set the gain about half way and the other setting around the same as the clean (depending the need of distortion).As far as the Solo channel goes I don't use it much other than at playing around at home. I just turn the volume up on the Rythm channel when I get the rare chance of soloing. I hope this helps, but I would suggest to play around with until u get the tone that u like :)
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